I should probably know this by now. But I'm a combine honours english and theatre and film and the Shakespeare course is English and Theatre and Film. Last year I took it as an english. Is it possible to take it again as a theatre and film course. my defense is that this year its a completely different set up than last year, different readings, different prof etc. Assuming the answer is generally no, who could I go to make a case?

I think its safe to assume that you can't... if you did this mark would replace the one you got last year.

You could take it again, but it would just look like a repeat of the course, so there's no real point. The grade doesn't replace the old one, you'll just have both on your transcript.