Medical Radiation Sciences I Course Requirements
The above link will give you course descriptions of the courses you will be taking. I cannot comment on difficulty of most courses except Cell Bio and Math but looking at the second year specializations, they do say that a minimum of a 5.0 (63-66%) GPA is required but since these are all limited enrolment programs, possession of the minimum requirements does not guarantee admission.
Bio may be a bit harder for lot of people simply because they've introduced online modules (online lectures) and you do it before coming to class. I've noticed that this makes it really really easy to fall behind. Each module is about 40-50 minutes long like a regular lecture but they pack so much information in one lecture that I remember each module took me about 2-3 hours to actually take notes and understand what was being said. There are two lectures a week compared to other courses that have three lectures a week (because online modules count as a class). Your first lecture is a review lecture where the prof will go over briefly the material that was covered in the week's module and answer questions and perhaps add a bit more info. The following lecture is an applied lecture where you study where these concepts are being applied in the real world and experiments and other relevent research conducted regarding this topic. Applied lecture content is heavily tested and are usually short answer format so definitely know that material well and don't skip applied lectures.